{
 "query": "sulfacetamide / sulfur",
 "ingredient": "sulfacetamide / sulfur",
 "slug": "sulfacetamide-sulfur",
 "rxcui": "690740",
 "brands": [
  "Avar",
  "BP 10-Wash",
  "BP Cleansing Wash",
  "Clenia",
  "Plexion",
  "Rosanil",
  "Rosula",
  "Sumadan Wash",
  "Sumaxin"
 ],
 "names": [
  "sulfacetamide / sulfur"
 ],
 "components": [
  {
   "ingredient": "sulfacetamide",
   "slug": "sulfacetamide",
   "grade": "B",
   "total": 80,
   "scores": {
    "safety": "A",
    "evidence": "F",
    "regulatory": "A",
    "conflict": "A",
    "options": "A"
   },
   "boxed": false,
   "controlled": false,
   "first_approval_fmt": "07/21/1946",
   "first_approval": "19460721"
  },
  {
   "ingredient": "sulfur",
   "slug": "sulfur",
   "grade": "A",
   "total": 88,
   "scores": {
    "safety": "A",
    "evidence": "D",
    "regulatory": "A",
    "conflict": "A",
    "options": "A"
   },
   "boxed": false,
   "controlled": false,
   "first_approval_fmt": "09/17/1940",
   "first_approval": "19400917"
  }
 ],
 "classes": [],
 "alternatives": [],
 "label": {},
 "faers": null,
 "faers_base": {
  "total": 20692304,
  "serious_share": 0.5742697381596559,
  "death_share": 0.09102355155810585
 },
 "recalls": [],
 "recall_total": 0,
 "drugsfda": {
  "first_approval": "19400917",
  "first_approval_fmt": "",
  "anda": 0,
  "nda": 0,
  "rems": false,
  "labeling_recent": 0
 },
 "trials": null,
 "pubmed": null,
 "payments": {
  "year": "2024",
  "usd": 2450.0,
  "records": 9,
  "by_name": [
   [
    "Sumadan Wash",
    2450.0
   ]
  ],
  "names_checked": [
   "sulfacetamide / sulfur",
   "Avar",
   "BP 10-Wash",
   "BP Cleansing Wash",
   "Clenia",
   "Plexion",
   "Rosanil",
   "Rosula",
   "Sumadan Wash",
   "Sumaxin"
  ],
  "source": "bulk-index"
 },
 "partd": {
  "year": "2024",
  "claims": 263,
  "beneficiaries": 162,
  "spend": 61722.56,
  "by_brand": [
   {
    "brand": "Sodium Sulfacetamide-Sulfur",
    "claims": 263,
    "per_claim": 234.68653992,
    "is_generic": false
   }
  ],
  "per_claim": 234.68653992395437
 },
 "mdl": [],
 "dsc": [],
 "settlements": [],
 "prescrire": null,
 "eml": null,
 "exposure": null,
 "scores": {
  "safety": {
   "score": 100,
   "letter": "A",
   "why": [
    "Graded by its riskiest ingredient, sulfacetamide (100)",
    "Death share in reports is near or below the FAERS average (0.3x)"
   ],
   "weight": 0.35
  },
  "evidence": {
   "score": 19,
   "letter": "F",
   "why": [
    "Graded by its riskiest ingredient, sulfacetamide (19)",
    "5 randomized trials and 0 systematic reviews/meta-analyses indexed in PubMed",
    "No Cochrane review found (-5)"
   ],
   "weight": 0.25
  },
  "regulatory": {
   "score": 100,
   "letter": "A",
   "why": [
    "Graded by its riskiest ingredient, sulfacetamide (100)",
    "No recalls on record since 2016"
   ],
   "weight": 0.15
  },
  "conflict": {
   "score": 100,
   "letter": "A",
   "why": [
    "Graded by its riskiest ingredient, sulfacetamide (100)",
    "Pharma paid doctors $0 tied to this drug last year: negligible",
    "Not named in any pending federal MDL"
   ],
   "weight": 0.15
  },
  "options": {
   "score": 90,
   "letter": "A",
   "why": [
    "Graded by its riskiest ingredient, sulfur (90)",
    "Sold over the counter under an FDA monograph: no application to approve, many makers",
    "2 same-class alternative(s) (-10)"
   ],
   "weight": 0.1
  }
 },
 "total": 79,
 "grade": "B",
 "questions": [
  "This is a fixed combination of sulfacetamide and sulfur. Why both together, instead of only the one I need?",
  "The most-reported problems in FDA's adverse event data are drug hypersensitivity, hypersensitivity, pain. How would we recognize and handle those?",
  "Why this one over chloramphenicol, clindamycin, erythromycin? What would make you pick one of those instead?",
  "What result are we expecting, by when, and what is the plan if it does not happen?",
  "If 100 people like me took this drug, how many would actually get better because of it, and how many would be harmed by it? (Doctors call these the number needed to treat and the number needed to harm.)",
  "The most-reported problems in FDA's adverse event data are dry skin, acne, erythema, skin burning sensation. How would we recognize and handle those?",
  "Why this one over mesulfen, tioxolone? What would make you pick one of those instead?",
  "There is no generic. Is there an older generic in the same class that works as well for my situation?"
 ]
}